The Age Tech: Epigenetic cosmetics

Epigenetic Modulation of the Skin: An Approach Focused on Regeneration

We formulated an anti-aging serum that stimulates the skin via epigenetic modulation to produce molecules decreasing with age. The objective is to obtain a regenerative effect at the cellular level and to prevent skin aging. This strategy reaches beyond the traditional approach of filling the deficiencies linked to aging skin.

What is Epigenetics?

Before understanding epigenetics, it is worth recalling that DNA contains our genetic material and therefore our genes which are DNA sequences. Genes are instructions given to cells to produce proteins. Proteins of interest for cosmetics include collagen and elastin, as their levels in skin decrease with age, while they are responsible for skin elasticity.

Finally, epigenetics is the term describing visible changes called “phenotypic” in which the DNA sequences are not modified. Epigenetics affect how genes are read by cells, and then how proteins make them. This process is called gene expression. Epigenetic modulation makes it possible to increase or decrease the expression of genes and their translation into proteins.

Cellular Reprogramming Against Skin Aging

With age, cells struggle to fight oxidative stress, genetic mutations accumulate In addition, gene expression becomes altered. Molecules responsible for skin elasticity are lacking and enzymes degrading them are over-activated. For example, skin collagen decreases by 1% per year from the age of 20. The result is a gradual decrease in elasticity, hydration and skin volume, leading to the appearance of fine lines, wrinkles, and then sagging of the face and body skin.

Given these parameters, we have applied the concept of epigenetic modulation to our in-depth knowledge of the mechanisms of skin cellular aging. Our goal is to stimulate DNA to produce molecules that decrease with age or to reduce the production of enzymes that degrade them.

Our active ingredients increase the synthesis of hyaluronic acid, collagen and elastin. The formulation also works on compounds that suppress the genetic expression of collagen-degrading enzymes. Beyond structural rejuvenation, and visible reduction of wrinkles, the gene expression profile is somehow reset or rejuvenated. Indeed, studies on these compounds show an increase in proteins stimulating regeneration by stem cells. In addition, tumor-suppressing proteins are decreased while the expression of antioxidant enzymes is increased.

Much more than an anti-wrinkle serum, The Age Tech revolutionizes cosmetics by acting on cellular reprogramming towards skin rejuvenation.

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